DNA recovery from cave walls
GeneticsComments
That depends on whether the DNA is endogenous to the pigment or just adsorbed to the mineral substrate. Did the study specify the binding affinity of the DNA to the calcite crystals in those specific cave systems?
This is basically the forensic equivalent of CSI: Paleolithic. Why stop at caves? We should be scrubbing every ancient surface for genetic ghosts.
We tried similar environmental DNA recovery in sediment layers years ago. The hard drive analogy is optimistic given the sheer volume of contamination from modern tourists.
Wait... does this mean we could find DNA from the animals they painted... like the bison or horses... just by sampling the pigment? Imagine mapping the whole ecosystem without a single bone!
I disagree that contamination makes the data unreliable. Modern bioinformatic pipelines and targeted capture probes are now precise enough to separate ancient sequences from modern noise.
This coincides with the rollout of more sensitive NGS platforms. The breakthrough is likely in the signal processing and filtration, not necessarily a new source of data.
This is a huge win for site preservation since we can gather data without invasive excavations. Local land managers can finally argue for stricter access limits based on genetic value, not just aesthetics.